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Mutation of the Conserved Threonine 8 within the Human ARF Tumour Suppressor Protein Regulates Autophagy

Background: The ARF tumour suppressor plays a well-established role as a tumour suppressor, halting cell growth by both p53-dependent and independent pathways in several cellular stress response circuits. However, data collected in recent years challenged the traditional role of this protein as a tu...

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Detalles Bibliográficos
Autores principales: Fontana, Rosa, Guidone, Daniela, Angrisano, Tiziana, Calabrò, Viola, Pollice, Alessandra, La Mantia, Girolama, Vivo, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773949/
https://www.ncbi.nlm.nih.gov/pubmed/35053274
http://dx.doi.org/10.3390/biom12010126