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Lactylated Histone H3K18 as a Potential Biomarker for the Diagnosis and Predicting the Severity of Septic Shock

OBJECTIVE: To date, there are no studies regarding the lactylation profile and its role in critically ill patients. Thus, we aimed to examine expression of histone H3 lysine 18 (H3K18) lactylation and its role in patients with septic shock. METHODS: Thirteen healthy volunteers and 35 critically ill...

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Detalles Bibliográficos
Autores principales: Chu, Xin, Di, Chenyi, Chang, Panpan, Li, Lina, Feng, Zhe, Xiao, Shirou, Yan, Xiaoyu, Xu, Xiaodong, Li, Hexin, Qi, Ruomei, Gong, Huan, Zhao, Yanyang, Xiao, Fei, Chang, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773995/
https://www.ncbi.nlm.nih.gov/pubmed/35069560
http://dx.doi.org/10.3389/fimmu.2021.786666