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Nicotinamide Inhibits T Cell Exhaustion and Increases Differentiation of CD8 Effector T Cells

SIMPLE SUMMARY: T cells that undergo repeated stimulation undergo a change called T cell exhaustion (TEx) that limits their ability to kill cancer cells and infections with microorganisms. The factors involved in the initiation and kinetics of these changes are poorly understood. In this research th...

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Detalles Bibliográficos
Autores principales: Alavi, Sara, Emran, Abdullah Al, Tseng, Hsin-Yi, Tiffen, Jessamy C., McGuire, Helen Marie, Hersey, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774026/
https://www.ncbi.nlm.nih.gov/pubmed/35053490
http://dx.doi.org/10.3390/cancers14020323