Cargando…
Nicotinamide Inhibits T Cell Exhaustion and Increases Differentiation of CD8 Effector T Cells
SIMPLE SUMMARY: T cells that undergo repeated stimulation undergo a change called T cell exhaustion (TEx) that limits their ability to kill cancer cells and infections with microorganisms. The factors involved in the initiation and kinetics of these changes are poorly understood. In this research th...
Autores principales: | Alavi, Sara, Emran, Abdullah Al, Tseng, Hsin-Yi, Tiffen, Jessamy C., McGuire, Helen Marie, Hersey, Peter |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774026/ https://www.ncbi.nlm.nih.gov/pubmed/35053490 http://dx.doi.org/10.3390/cancers14020323 |
Ejemplares similares
-
Do innate killing mechanisms activated by inflammasomes have a role in treating melanoma?
por: Emran, Abdullah Al, et al.
Publicado: (2020) -
Pretreatment Innate Cell Populations and CD4 T Cells in Blood Are Associated With Response to Immune Checkpoint Blockade in Melanoma Patients
por: Pirozyan, Mehdi R., et al.
Publicado: (2020) -
Lysine Demethylases: Promising Drug Targets in Melanoma and Other Cancers
por: Punnia-Moorthy, Gaya, et al.
Publicado: (2021) -
Sex bias of females in survival from cancer and infections. Is X the answer?
por: Emran, Abdullah Al, et al.
Publicado: (2021) -
Inducible but Not Constitutive Expression of PD-L1 in Human Melanoma Cells Is Dependent on Activation of NF-κB
por: Gowrishankar, Kavitha, et al.
Publicado: (2015)