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Synthesis and Validation of a Bioinspired Catechol-Functionalized Pt(IV) Prodrug for Preclinical Intranasal Glioblastoma Treatment

SIMPLE SUMMARY: Glioblastoma (GB) is a type of brain cancer with a poor prognosis and few improvements in its treatment. One of the greatest difficulties in GB therapy lies in the fact that most of the drugs with high anticancer potential do not reach the brain and exert high therapeutic activity wh...

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Detalles Bibliográficos
Autores principales: Mao, Xiaoman, Wu, Shuang, Calero-Pérez, Pilar, Candiota, Ana P., Alfonso, Paula, Bruna, Jordi, Yuste, Victor J., Lorenzo, Julia, Novio, Fernando, Ruiz-Molina, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774041/
https://www.ncbi.nlm.nih.gov/pubmed/35053575
http://dx.doi.org/10.3390/cancers14020410