Cargando…

Synthesis and Validation of a Bioinspired Catechol-Functionalized Pt(IV) Prodrug for Preclinical Intranasal Glioblastoma Treatment

SIMPLE SUMMARY: Glioblastoma (GB) is a type of brain cancer with a poor prognosis and few improvements in its treatment. One of the greatest difficulties in GB therapy lies in the fact that most of the drugs with high anticancer potential do not reach the brain and exert high therapeutic activity wh...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mao, Xiaoman, Wu, Shuang, Calero-Pérez, Pilar, Candiota, Ana P., Alfonso, Paula, Bruna, Jordi, Yuste, Victor J., Lorenzo, Julia, Novio, Fernando, Ruiz-Molina, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774041/ https://www.ncbi.nlm.nih.gov/pubmed/35053575 http://dx.doi.org/10.3390/cancers14020410

Ejemplares similares

Intranasal Administration of Catechol-Based Pt(IV) Coordination Polymer Nanoparticles for Glioblastoma Therapy
por: Mao, Xiaoman, et al.
Publicado: (2022)

Advances in Preclinical/Clinical Glioblastoma Treatment: Can Nanoparticles Be of Help?
por: Ruiz-Molina, Daniel, et al.
Publicado: (2022)

Bioinspired Theranostic Coordination Polymer Nanoparticles for Intranasal Dopamine Replacement in Parkinson’s Disease
por: García-Pardo, Javier, et al.
Publicado: (2021)

Bioinspired Catechol-Based Systems: Chemistry and Applications
por: d’Ischia, Marco, et al.
Publicado: (2017)

Pt(IV) Prodrugs with NSAIDs as Axial Ligands
por: Spector, Daniil, et al.
Publicado: (2021)

Anti-PD-1 Immunotherapy in Preclinical GL261 Glioblastoma: Influence of Therapeutic Parameters and Non-Invasive Response Biomarker Assessment with MRSI-Based Approaches
por: Wu, Shuang, et al.
Publicado: (2020)

Platinum-Based Nanoformulations for Glioblastoma Treatment: The Resurgence of Platinum Drugs?
por: Alfonso-Triguero, Paula, et al.
Publicado: (2023)

Current Developments in Pt(IV) Prodrugs Conjugated with Bioactive Ligands
por: Li, Xuejiao, et al.
Publicado: (2018)

Recent Advances in Light-Controlled Activation of Pt(IV) Prodrugs
por: Spector, Daniil, et al.
Publicado: (2022)

Encapsulation of Pt(iv) prodrugs within a Pt(ii) cage for drug delivery
por: Zheng, Yao-Rong, et al.
Publicado: (2015)

Immune System-Related Changes in Preclinical GL261 Glioblastoma under TMZ Treatment: Explaining MRSI-Based Nosological Imaging Findings with RT-PCR Analyses
por: Calero-Pérez, Pilar, et al.
Publicado: (2021)

Riboflavin as a bioorthogonal photocatalyst for the activation of a Pt(IV) prodrug
por: Alonso-de Castro, Silvia, et al.
Publicado: (2017)

An intramolecular photoswitch can significantly promote photoactivation of Pt(iv) prodrugs
por: Deng, Zhiqin, et al.
Publicado: (2021)

Biological activity of Pt(IV) prodrugs triggered by riboflavin-mediated bioorthogonal photocatalysis
por: Alonso-de Castro, Silvia, et al.
Publicado: (2018)

Can the Self-Assembling of Dicarboxylate Pt(IV) Prodrugs Influence Their Cell Uptake?
por: Ravera, Mauro, et al.
Publicado: (2021)

Image-Guided Nanodelivery of Pt(IV) Prodrugs to GRP-Receptor Positive Tumors
por: Silva, Francisco, et al.
Publicado: (2023)

Bioinspired Oxidation-Resistant Catechol-like Sliding Ring Polyrotaxane Hydrogels
por: Rial-Hermida, M. Isabel, et al.
Publicado: (2023)

Improvement of Kiteplatin Efficacy by a Benzoato Pt(IV) Prodrug Suitable for Oral Administration
por: Barbanente, Alessandra, et al.
Publicado: (2022)

Magnetic Catechol-Chitosan with Bioinspired Adhesive Surface: Preparation and Immobilization of ω-Transaminase
por: Ni, Kefeng, et al.
Publicado: (2012)

Pt(IV) Prodrugs Designed to Bind Non-Covalently to Human Serum Albumin for Drug Delivery
por: Zheng, Yao-Rong, et al.
Publicado: (2014)

Photopolymerized 3D Printing Scaffolds with Pt(IV) Prodrug Initiator for Postsurgical Tumor Treatment
por: Zhang, Qingfei, et al.
Publicado: (2022)

Cell-Adhesive Bioinspired and Catechol-Based Multilayer Freestanding Membranes for Bone Tissue Engineering
por: Sousa, Maria P., et al.
Publicado: (2017)

Pt(IV) prodrug initiated microparticles from microfluidics for tumor chemo-, photothermal and photodynamic combination therapy
por: Zhang, Qingfei, et al.
Publicado: (2022)

Structure elucidation and quantification of the reduction products of anticancer Pt(iv) prodrugs by electrochemistry/mass spectrometry (EC-MS)
por: Frensemeier, L. M., et al.
Publicado: (2018)

Facile Synthesis of a Pt(IV) Prodrug of Cisplatin and Its Intrinsically (195m)Pt Labeled Analog: A Step Closer to Cancer Theranostic
por: Sharma, K. Shitaljit, et al.
Publicado: (2021)

A Pt(IV) Prodrug Combining Chlorambucil and Cisplatin: A Dual-Acting Weapon for Targeting DNA in Cancer Cells
por: Montagner, Diego, et al.
Publicado: (2018)

Investigations of the Kinetics and Mechanism of Reduction of a Carboplatin Pt(IV) Prodrug by the Major Small-Molecule Reductants in Human Plasma
por: Liu, Yang, et al.
Publicado: (2019)

Potent Chlorambucil-Platinum(IV) Prodrugs
por: Aputen, Angelico D., et al.
Publicado: (2022)

A pH-responsive liposomal nanoplatform for co-delivery of a Pt(IV) prodrug and cinnamaldehyde for effective tumor therapy
por: Tang, Ting, et al.
Publicado: (2023)

Dioxygen Activation by a Bioinspired Tungsten(IV) Complex
por: Ćorović, Miljan Z., et al.
Publicado: (2023)

Successful Partnerships: Exploring the Potential of Immunogenic Signals Triggered by TMZ, CX-4945, and Combined Treatment in GL261 Glioblastoma Cells
por: Villamañan, Lucía, et al.
Publicado: (2021)

Comprehensive Vibrational Spectroscopic Investigation of trans,trans,trans-[Pt(N(3))(2)(OH)(2)(py)(2)], a Pt(IV) Diazido Anticancer Prodrug Candidate
por: Vernooij, Robbin R., et al.
Publicado: (2016)

Bioinspired Catechol‐Grafting PEDOT Cathode for an All‐Polymer Aqueous Proton Battery with High Voltage and Outstanding Rate Capacity
por: Zhu, Meihua, et al.
Publicado: (2021)

Cellular Toxicity Mechanisms and the Role of Autophagy in Pt(IV) Prodrug-Loaded Ultrasmall Iron Oxide Nanoparticles Used for Enhanced Drug Delivery
por: Gutiérrez-Romero, L., et al.
Publicado: (2021)

Novel Pt(IV) prodrug self-assembled nanoparticles with enhanced blood circulation stability and improved antitumor capacity of oxaliplatin for cancer therapy
por: Fu, Yuanlei, et al.
Publicado: (2023)

Metal-Free Radical Dendrimers as MRI Contrast Agents for Glioblastoma Diagnosis: Ex Vivo and In Vivo Approaches
por: Zhang, Songbai, et al.
Publicado: (2022)

Synthesis and Reactivity of a Bioinspired Molybdenum(IV) Acetylene Complex
por: Ehweiner, Madeleine A., et al.
Publicado: (2021)

Kaxiras’s Porphyrin: DFT Modeling of Redox-Tuned Optical and Electronic Properties in a Theoretically Designed Catechol-Based Bioinspired Platform
por: Crescenzi, Orlando, et al.
Publicado: (2017)

Ligand Evolution in the Photoactivatable Platinum(IV) Anticancer Prodrugs
por: Huang, Jingjing, et al.
Publicado: (2022)

Repurposing Platinum(IV) Prodrugs to Modulate Mitochondrial Metabolism
por: Zacharioudakis, Emmanouil, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_75lkj759164qeasmq2rfk2t165