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SARS-CoV-2 Omicron variant shows less efficient replication and fusion activity when compared with Delta variant in TMPRSS2-expressed cells

The novel SARS-CoV-2 Omicron variant (B.1.1.529), first found in early November 2021, has sparked considerable global concern and it has >50 mutations, many of which are known to affect transmissibility or cause immune escape. In this study, we sought to investigate the virological characteristic...

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Detalles Bibliográficos
Autores principales: Zhao, Hanjun, Lu, Lu, Peng, Zheng, Chen, Lin-Lei, Meng, Xinjin, Zhang, Chuyuan, Ip, Jonathan Daniel, Chan, Wan-Mui, Chu, Allen Wing-Ho, Chan, Kwok-Hung, Jin, Dong-Yan, Chen, Honglin, Yuen, Kwok-Yung, To, Kelvin Kai-Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774049/
https://www.ncbi.nlm.nih.gov/pubmed/34951565
http://dx.doi.org/10.1080/22221751.2021.2023329