RNA Molecular Signature Profiling in PBMCs of Sporadic ALS Patients: HSP70 Overexpression Is Associated with Nuclear SOD1

Superoxide dismutase 1 (SOD1) is one of the causative genes associated with amyotrophic lateral sclerosis (ALS), a neurodegenerative disorder. SOD1 aggregation contributes to ALS pathogenesis. A fraction of the protein is localized in the nucleus (nSOD1), where it seems to be involved in the regulat...

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Detalles Bibliográficos
Autores principales: Garofalo, Maria, Pandini, Cecilia, Bordoni, Matteo, Jacchetti, Emanuela, Diamanti, Luca, Carelli, Stephana, Raimondi, Manuela Teresa, Sproviero, Daisy, Crippa, Valeria, Carra, Serena, Poletti, Angelo, Pansarasa, Orietta, Gagliardi, Stella, Cereda, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774074/
https://www.ncbi.nlm.nih.gov/pubmed/35053410
http://dx.doi.org/10.3390/cells11020293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774074/
https://www.ncbi.nlm.nih.gov/pubmed/35053410
http://dx.doi.org/10.3390/cells11020293

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