Calcium Signaling Pathway Is Involved in the Shedding of ACE2 Catalytic Ectodomain: New Insights for Clinical and Therapeutic Applications of ACE2 for COVID-19

The angiotensin-converting enzyme 2 (ACE2) is a type I integral membrane that exists in two forms: the first is a transmembrane protein; the second is a soluble catalytic ectodomain of ACE2. The catalytic ectodomain of ACE2 undergoes shedding by a disintegrin and metalloproteinase domain-containing...

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Detalles Bibliográficos
Autores principales: García-Escobar, Artemio, Vera-Vera, Silvio, Jurado-Román, Alfonso, Jiménez-Valero, Santiago, Galeote, Guillermo, Moreno, Raúl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774087/
https://www.ncbi.nlm.nih.gov/pubmed/35053224
http://dx.doi.org/10.3390/biom12010076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774087/
https://www.ncbi.nlm.nih.gov/pubmed/35053224
http://dx.doi.org/10.3390/biom12010076

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