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Calcium Signaling Pathway Is Involved in the Shedding of ACE2 Catalytic Ectodomain: New Insights for Clinical and Therapeutic Applications of ACE2 for COVID-19

The angiotensin-converting enzyme 2 (ACE2) is a type I integral membrane that exists in two forms: the first is a transmembrane protein; the second is a soluble catalytic ectodomain of ACE2. The catalytic ectodomain of ACE2 undergoes shedding by a disintegrin and metalloproteinase domain-containing...

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Detalles Bibliográficos
Autores principales:	García-Escobar, Artemio, Vera-Vera, Silvio, Jurado-Román, Alfonso, Jiménez-Valero, Santiago, Galeote, Guillermo, Moreno, Raúl
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774087/ https://www.ncbi.nlm.nih.gov/pubmed/35053224 http://dx.doi.org/10.3390/biom12010076

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