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Comprehensive Analysis of Co-Mutations Identifies Cooperating Mechanisms of Tumorigenesis

SIMPLE SUMMARY: Somatic mutations are one of the most important causal factors of cancers. In this study, we show that certain mutations, when occurring simultaneously, have a stronger biological effect than their single counterpart. These effects include prognosis and drug sensitivity. ABSTRACT: So...

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Detalles Bibliográficos
Autores principales: Jiang, Limin, Yu, Hui, Ness, Scott, Mao, Peng, Guo, Fei, Tang, Jijun, Guo, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774165/
https://www.ncbi.nlm.nih.gov/pubmed/35053577
http://dx.doi.org/10.3390/cancers14020415