Nuclear Fragility in Radiation-Induced Senescence: Blebs and Tubes Visualized by 3D Electron Microscopy

Irreparable DNA damage following ionizing radiation (IR) triggers prolonged DNA damage response and induces premature senescence. Cellular senescence is a permanent state of cell-cycle arrest characterized by chromatin restructuring, altered nuclear morphology and acquisition of secretory phenotype,...

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Detalles Bibliográficos
Autores principales: Freyter, Benjamin M., Abd Al-razaq, Mutaz A., Isermann, Anna, Dietz, Anne, Azimzadeh, Omid, Hekking, Liesbeth, Gomolka, Maria, Rübe, Claudia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774169/
https://www.ncbi.nlm.nih.gov/pubmed/35053389
http://dx.doi.org/10.3390/cells11020273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774169/
https://www.ncbi.nlm.nih.gov/pubmed/35053389
http://dx.doi.org/10.3390/cells11020273

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