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Treadmill Exercise Prevents Decline in Spatial Learning and Memory in 3×Tg-AD Mice through Enhancement of Structural Synaptic Plasticity of the Hippocampus and Prefrontal Cortex

Alzheimer’s disease (AD) is characterized by deficits in learning and memory. A pathological feature of AD is the alterations in the number and size of synapses, axon length, dendritic complexity, and dendritic spine numbers in the hippocampus and prefrontal cortex. Treadmill exercise can enhance sy...

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Detalles Bibliográficos
Autores principales: Mu, Lianwei, Cai, Jiajia, Gu, Boya, Yu, Laikang, Li, Cui, Liu, Qing-Song, Zhao, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774241/
https://www.ncbi.nlm.nih.gov/pubmed/35053360
http://dx.doi.org/10.3390/cells11020244