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PRMT1 Regulates EGFR and Wnt Signaling Pathways and Is a Promising Target for Combinatorial Treatment of Breast Cancer

SIMPLE SUMMARY: Patients with triple-negative breast cancer (TNBC) respond well to chemotherapy initially but are prone to relapse. Searching for new therapeutic targets, we found that PRMT1 is highly expressed in TNBC tumor samples and is essential for breast cancer cell survival. Furthermore, this...

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Detalles Bibliográficos
Autores principales: Suresh, Samyuktha, Huard, Solène, Brisson, Amélie, Némati, Fariba, Dakroub, Rayan, Poulard, Coralie, Ye, Mengliang, Martel, Elise, Reyes, Cécile, Silvestre, David C., Meseure, Didier, Nicolas, André, Gentien, David, Fayyad-Kazan, Hussein, Le Romancer, Muriel, Decaudin, Didier, Roman-Roman, Sergio, Dubois, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774276/
https://www.ncbi.nlm.nih.gov/pubmed/35053470
http://dx.doi.org/10.3390/cancers14020306