Cargando…
PRMT1 Regulates EGFR and Wnt Signaling Pathways and Is a Promising Target for Combinatorial Treatment of Breast Cancer
SIMPLE SUMMARY: Patients with triple-negative breast cancer (TNBC) respond well to chemotherapy initially but are prone to relapse. Searching for new therapeutic targets, we found that PRMT1 is highly expressed in TNBC tumor samples and is essential for breast cancer cell survival. Furthermore, this...
Autores principales: | Suresh, Samyuktha, Huard, Solène, Brisson, Amélie, Némati, Fariba, Dakroub, Rayan, Poulard, Coralie, Ye, Mengliang, Martel, Elise, Reyes, Cécile, Silvestre, David C., Meseure, Didier, Nicolas, André, Gentien, David, Fayyad-Kazan, Hussein, Le Romancer, Muriel, Decaudin, Didier, Roman-Roman, Sergio, Dubois, Thierry |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774276/ https://www.ncbi.nlm.nih.gov/pubmed/35053470 http://dx.doi.org/10.3390/cancers14020306 |
Ejemplares similares
-
Therapeutic Advantage of Targeting PRMT5 in Combination with Chemotherapies or EGFR/HER2 Inhibitors in Triple-Negative Breast Cancers
por: Dakroub, Rayan, et al.
Publicado: (2023) -
Expression, Localization and Prognosis Association of MEP50 in Breast Cancer
por: Suresh, Samyuktha, et al.
Publicado: (2022) -
PRMT5 prognostic value in cancer
por: Lattouf, Hanine, et al.
Publicado: (2019) -
Structure, Activity, and Function of PRMT1
por: Thiebaut, Charlène, et al.
Publicado: (2021) -
Protein arginine methyltransferase 5: A novel therapeutic target for triple‐negative breast cancers
por: Vinet, Mathilde, et al.
Publicado: (2019)