The Longevity-Associated Variant of BPIFB4 Reduces Senescence in Glioma Cells and in Patients’ Lymphocytes Favoring Chemotherapy Efficacy

Glioblastoma (GBM) is the most common primary brain cancer with the median age at diagnosis around 64 years, thus pointing to aging as an important risk factor. Indeed, aging, by increasing the senescence burden, is configured as a negative prognostic factor for GBM stage. Furthermore, several anti-...

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Detalles Bibliográficos
Autores principales: Puca, Annibale Alessandro, Lopardo, Valentina, Montella, Francesco, Di Pietro, Paola, Cesselli, Daniela, Rolle, Irene Giulia, Bulfoni, Michela, Di Sarno, Veronica, Iaconetta, Giorgio, Campiglia, Pietro, Vecchione, Carmine, Beltrami, Antonio Paolo, Ciaglia, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774353/
https://www.ncbi.nlm.nih.gov/pubmed/35053408
http://dx.doi.org/10.3390/cells11020294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774353/
https://www.ncbi.nlm.nih.gov/pubmed/35053408
http://dx.doi.org/10.3390/cells11020294

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