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The Longevity-Associated Variant of BPIFB4 Reduces Senescence in Glioma Cells and in Patients’ Lymphocytes Favoring Chemotherapy Efficacy
Glioblastoma (GBM) is the most common primary brain cancer with the median age at diagnosis around 64 years, thus pointing to aging as an important risk factor. Indeed, aging, by increasing the senescence burden, is configured as a negative prognostic factor for GBM stage. Furthermore, several anti-...
Autores principales: | Puca, Annibale Alessandro, Lopardo, Valentina, Montella, Francesco, Di Pietro, Paola, Cesselli, Daniela, Rolle, Irene Giulia, Bulfoni, Michela, Di Sarno, Veronica, Iaconetta, Giorgio, Campiglia, Pietro, Vecchione, Carmine, Beltrami, Antonio Paolo, Ciaglia, Elena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774353/ https://www.ncbi.nlm.nih.gov/pubmed/35053408 http://dx.doi.org/10.3390/cells11020294 |
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