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Wnt Signaling Rescues Amyloid Beta-Induced Gut Stem Cell Loss

Patients with Alzheimer’s disease suffer from a decrease in brain mass and a prevalence of amyloid-β plaques. These plaques are thought to play a role in disease progression, but their exact role is not entirely established. We developed an optogenetic model to induce amyloid-β intracellular oligome...

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Detalles Bibliográficos
Autores principales: Kaur, Prameet, Chua, Ellora Hui Zhen, Lim, Wen Kin, Liu, Jiarui, Harmston, Nathan, Tolwinski, Nicholas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774390/
https://www.ncbi.nlm.nih.gov/pubmed/35053396
http://dx.doi.org/10.3390/cells11020281