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Polyunsaturated Fatty Acids as Prebiotics: Innovation or Confirmation?
The International Scientific Association for Probiotics and Prebiotics (ISAPP), in its last consensus statement about prebiotics, defined polyunsaturated fatty acids (PUFAs) as “candidate prebiotics” due to a lack of complete scientific evidence. Previous studies have demonstrated the ability of mic...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774454/ https://www.ncbi.nlm.nih.gov/pubmed/35053879 http://dx.doi.org/10.3390/foods11020146 |
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author | Rinninella, Emanuele Costantini, Lara |
author_facet | Rinninella, Emanuele Costantini, Lara |
author_sort | Rinninella, Emanuele |
collection | PubMed |
description | The International Scientific Association for Probiotics and Prebiotics (ISAPP), in its last consensus statement about prebiotics, defined polyunsaturated fatty acids (PUFAs) as “candidate prebiotics” due to a lack of complete scientific evidence. Previous studies have demonstrated the ability of microbiota to metabolize PUFAs, although the role of the resulting metabolites in the host is less known. Recent partial evidence shows that these metabolites can have important health effects in the host, reinforcing the concept of the prebiotic action of PUFAs, despite the data being mostly related to omega-6 linoleic acid and to lactobacilli taxon. However, considering that the symbionts in our gut benefit from the nutritional molecules that we include in our diet, and that bacteria, like all living organisms, cannot benefit from a single nutritional molecule, the concept of the “correct prebiotic diet” should be the new frontier in the field of gut microbiota research. |
format | Online Article Text |
id | pubmed-8774454 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87744542022-01-21 Polyunsaturated Fatty Acids as Prebiotics: Innovation or Confirmation? Rinninella, Emanuele Costantini, Lara Foods Commentary The International Scientific Association for Probiotics and Prebiotics (ISAPP), in its last consensus statement about prebiotics, defined polyunsaturated fatty acids (PUFAs) as “candidate prebiotics” due to a lack of complete scientific evidence. Previous studies have demonstrated the ability of microbiota to metabolize PUFAs, although the role of the resulting metabolites in the host is less known. Recent partial evidence shows that these metabolites can have important health effects in the host, reinforcing the concept of the prebiotic action of PUFAs, despite the data being mostly related to omega-6 linoleic acid and to lactobacilli taxon. However, considering that the symbionts in our gut benefit from the nutritional molecules that we include in our diet, and that bacteria, like all living organisms, cannot benefit from a single nutritional molecule, the concept of the “correct prebiotic diet” should be the new frontier in the field of gut microbiota research. MDPI 2022-01-06 /pmc/articles/PMC8774454/ /pubmed/35053879 http://dx.doi.org/10.3390/foods11020146 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Commentary Rinninella, Emanuele Costantini, Lara Polyunsaturated Fatty Acids as Prebiotics: Innovation or Confirmation? |
title | Polyunsaturated Fatty Acids as Prebiotics: Innovation or Confirmation? |
title_full | Polyunsaturated Fatty Acids as Prebiotics: Innovation or Confirmation? |
title_fullStr | Polyunsaturated Fatty Acids as Prebiotics: Innovation or Confirmation? |
title_full_unstemmed | Polyunsaturated Fatty Acids as Prebiotics: Innovation or Confirmation? |
title_short | Polyunsaturated Fatty Acids as Prebiotics: Innovation or Confirmation? |
title_sort | polyunsaturated fatty acids as prebiotics: innovation or confirmation? |
topic | Commentary |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774454/ https://www.ncbi.nlm.nih.gov/pubmed/35053879 http://dx.doi.org/10.3390/foods11020146 |
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