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Identification of Hotspot Mutations in the N Gene of SARS-CoV-2 in Russian Clinical Samples That May Affect the Detection by Reverse Transcription-PCR

Sensitive and reliable diagnostic test systems based on real-time PCR are of great importance in the fight against the ongoing SARS-CoV-2 pandemic. The genetic variability of the SARS-CoV-2 virus leads to the accumulation of mutations, some of which may affect the sensitivity of modern PCR assays. T...

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Detalles Bibliográficos
Autores principales: Kiryanov, Sergei A., Levina, Tatiana A., Konopleva, Maria V., Suslov, Anatoly P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774456/
https://www.ncbi.nlm.nih.gov/pubmed/35054314
http://dx.doi.org/10.3390/diagnostics12010147