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Fine Mapping of the Mouse Ath28 Locus Yields Three Atherosclerosis Modifying Sub-Regions

A mouse strain intercross between Apoe(−/−) AKR/J and DBA/2J mice identified three replicated atherosclerosis quantitative trait loci (QTLs). Our objective was to fine map mouse atherosclerosis modifier genes within a genomic region known to affect lesion development in apoE-deficient (Apoe(−/−)) mi...

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Detalles Bibliográficos
Autores principales: Han, Juying, Ritchey, Brian, Opoku, Emmanuel, Smith, Jonathan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774523/
https://www.ncbi.nlm.nih.gov/pubmed/35052410
http://dx.doi.org/10.3390/genes13010070