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Peptide-Mucin Binding and Biosimilar Mucus-Permeating Properties

This study aimed to understand the role of the mucus layer (a biological hydrogel) in the transport mechanisms of peptides. Using established in vitro models, the mucin-binding activity and mucus-permeating property of peptides were determined. Uncharged peptides with relatively high hydrophilicity,...

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Detalles Bibliográficos
Autores principales: Sun, Xiaohong, Abioye, Raliat O., Okagu, Ogadimma D., Udenigwe, Chibuike C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774657/
https://www.ncbi.nlm.nih.gov/pubmed/35049536
http://dx.doi.org/10.3390/gels8010001