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Peptide-Mucin Binding and Biosimilar Mucus-Permeating Properties
This study aimed to understand the role of the mucus layer (a biological hydrogel) in the transport mechanisms of peptides. Using established in vitro models, the mucin-binding activity and mucus-permeating property of peptides were determined. Uncharged peptides with relatively high hydrophilicity,...
Autores principales: | Sun, Xiaohong, Abioye, Raliat O., Okagu, Ogadimma D., Udenigwe, Chibuike C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774657/ https://www.ncbi.nlm.nih.gov/pubmed/35049536 http://dx.doi.org/10.3390/gels8010001 |
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