Inhibitory Mechanism of Baicalein on Acetylcholinesterase: Inhibitory Interaction, Conformational Change, and Computational Simulation

Alzheimer’s disease (AD) is the most prevalent chronic neurodegenerative disease in elderly individuals, causing dementia. Acetylcholinesterase (AChE) is regarded as one of the most popular drug targets for AD. Herbal secondary metabolites are frequently cited as a major source of AChE inhibitors. I...

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Detalles Bibliográficos
Autores principales: Liao, Yijing, Hu, Xing, Pan, Junhui, Zhang, Guowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774682/
https://www.ncbi.nlm.nih.gov/pubmed/35053900
http://dx.doi.org/10.3390/foods11020168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774682/
https://www.ncbi.nlm.nih.gov/pubmed/35053900
http://dx.doi.org/10.3390/foods11020168

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