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Clozapine-Encapsulated Binary Mixed Micelles in Thermosensitive Sol–Gels for Intranasal Administration

(1) Background: Clozapine is the most effective antipsychotic. It is, however, associated with many adverse drug reactions. Nose-to-brain (N2B) delivery offers a promising approach. This study aims to develop clozapine-encapsulated thermosensitive sol–gels for N2B delivery. (2) Methods: Poloxamer 40...

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Detalles Bibliográficos
Autores principales: Tan, Madeleine S. A., Pandey, Preeti, Falconer, James R., Siskind, Dan J., Balmanno, Alexandra, Parekh, Harendra S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774880/
https://www.ncbi.nlm.nih.gov/pubmed/35049572
http://dx.doi.org/10.3390/gels8010038