Single-Cell Analysis of Aneurysmal Aortic Tissue in Patients with Marfan Syndrome Reveals Dysfunctional TGF-β Signaling

The molecular and cellular processes leading to aortic aneurysm development in Marfan syndrome (MFS) remain poorly understood. In this study, we examined the changes of aortic cell populations and gene expression in MFS by performing single-cell RNA sequencing (scRNA seq) on ascending aortic aneurys...

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Detalles Bibliográficos
Autores principales: Dawson, Ashley, Li, Yanming, Li, Yang, Ren, Pingping, Vasquez, Hernan G., Zhang, Chen, Rebello, Kimberly R., Ageedi, Waleed, Azares, Alon R., Mattar, Aladdein Burchett, Sheppard, Mary Burchett, Lu, Hong S., Coselli, Joseph S., Cassis, Lisa A., Daugherty, Alan, Shen, Ying H., LeMaire, Scott A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774900/
https://www.ncbi.nlm.nih.gov/pubmed/35052435
http://dx.doi.org/10.3390/genes13010095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774900/
https://www.ncbi.nlm.nih.gov/pubmed/35052435
http://dx.doi.org/10.3390/genes13010095

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