Accuracy and Clinical Relevance of Intra-Tumoral Fusobacterium nucleatum Detection in Formalin-Fixed Paraffin-Embedded (FFPE) Tissue by Droplet Digital PCR (ddPCR) in Colorectal Cancer

The use of droplet digital PCR (ddPCR) to identify and quantify low-abundance targets is a significant advantage for accurately detecting potentially oncogenic bacteria. Fusobacterium nucleatum (Fn) is implicated in colorectal cancer (CRC) tumorigenesis and is becoming an important prognostic biomar...

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Autores principales: Datorre, José Guilherme, de Carvalho, Ana Carolina, dos Reis, Mariana Bisarro, dos Reis, Monise, Matsushita, Marcus, Santos, Florinda, Guimarães, Denise Peixoto, Reis, Rui Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775036/
https://www.ncbi.nlm.nih.gov/pubmed/35054281
http://dx.doi.org/10.3390/diagnostics12010114