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Accuracy and Clinical Relevance of Intra-Tumoral Fusobacterium nucleatum Detection in Formalin-Fixed Paraffin-Embedded (FFPE) Tissue by Droplet Digital PCR (ddPCR) in Colorectal Cancer
The use of droplet digital PCR (ddPCR) to identify and quantify low-abundance targets is a significant advantage for accurately detecting potentially oncogenic bacteria. Fusobacterium nucleatum (Fn) is implicated in colorectal cancer (CRC) tumorigenesis and is becoming an important prognostic biomar...
Autores principales: | Datorre, José Guilherme, de Carvalho, Ana Carolina, dos Reis, Mariana Bisarro, dos Reis, Monise, Matsushita, Marcus, Santos, Florinda, Guimarães, Denise Peixoto, Reis, Rui Manuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775036/ https://www.ncbi.nlm.nih.gov/pubmed/35054281 http://dx.doi.org/10.3390/diagnostics12010114 |
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