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Osteocytic Pericellular Matrix (PCM): Accelerated Degradation under In Vivo Loading and Unloading Conditions Using a Novel Imaging Approach

The proteoglycan-containing pericellular matrix (PCM) controls both the biophysical and biochemical microenvironment of osteocytes, which are the most abundant cells embedded and dispersed in bones. As a molecular sieve, osteocytic PCMs not only regulate mass transport to and from osteocytes but als...

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Detalles Bibliográficos
Autores principales: Pei, Shaopeng, Wang, Shubo, Martinez, Jerahme R., Parajuli, Ashutosh, Kirn-Safran, Catherine B., Farach-Carson, Mary C., Lu, X. Lucas, Wang, Liyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775093/
https://www.ncbi.nlm.nih.gov/pubmed/35052411
http://dx.doi.org/10.3390/genes13010072