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Enhanced β-adrenergic response in mice with dominant-negative expression of the PKD2L1 channel

Polycystic kidney disease (PKD) is the most common genetic cause of kidney failure in humans. Among the various PKD-related molecules, PKD2L1 forms cation channels, but its physiological importance is obscure. In the present study, we established a transgenic mouse line by overexpressing the dominan...

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Detalles Bibliográficos
Autores principales: Murakami, Manabu, Murakami, Agnieszka M., Nemoto, Takayuki, Ohba, Takayoshi, Yonekura, Manabu, Toyama, Yuichi, Tomita, Hirofumi, Matsuzaki, Yasushi, Sawamura, Daisuke, Hirota, Kazuyoshi, Itagaki, Shirou, Asada, Yujiro, Miyoshi, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775249/
https://www.ncbi.nlm.nih.gov/pubmed/35051185
http://dx.doi.org/10.1371/journal.pone.0261668