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Enhanced β-adrenergic response in mice with dominant-negative expression of the PKD2L1 channel
Polycystic kidney disease (PKD) is the most common genetic cause of kidney failure in humans. Among the various PKD-related molecules, PKD2L1 forms cation channels, but its physiological importance is obscure. In the present study, we established a transgenic mouse line by overexpressing the dominan...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775249/ https://www.ncbi.nlm.nih.gov/pubmed/35051185 http://dx.doi.org/10.1371/journal.pone.0261668 |