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Meta-Analysis of Transcriptome-Wide Association Studies across 13 Brain Tissues Identified Novel Clusters of Genes Associated with Nicotine Addiction

Genome-wide association studies (GWAS) have identified and reproduced thousands of diseases associated loci, but many of them are not directly interpretable due to the strong linkage disequilibrium among variants. Transcriptome-wide association studies (TWAS) incorporated expression quantitative tra...

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Detalles Bibliográficos
Autores principales: Ye, Zhenyao, Mo, Chen, Ke, Hongjie, Yan, Qi, Chen, Chixiang, Kochunov, Peter, Hong, L. Elliot, Mitchell, Braxton D., Chen, Shuo, Ma, Tianzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775257/
https://www.ncbi.nlm.nih.gov/pubmed/35052378
http://dx.doi.org/10.3390/genes13010037