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Genome-Wide Analysis in Drosophila Reveals the Genetic Basis of Variation in Age-Specific Physical Performance and Response to ACE Inhibition

Despite impressive results in restoring physical performance in rodent models, treatment with renin–angiotensin system (RAS) inhibitors, such as Lisinopril, have highly mixed results in humans, likely, in part, due to genetic variation in human populations. To date, the genetic determinants of respo...

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Detalles Bibliográficos
Autores principales: Gabrawy, Mariann M., Khosravian, Nick, Morcos, George S., Morozova, Tatiana V., Jezek, Meagan, Walston, Jeremy D., Huang, Wen, Abadir, Peter M., Leips, Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775566/
https://www.ncbi.nlm.nih.gov/pubmed/35052483
http://dx.doi.org/10.3390/genes13010143