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Genome-Wide Analysis in Drosophila Reveals the Genetic Basis of Variation in Age-Specific Physical Performance and Response to ACE Inhibition
Despite impressive results in restoring physical performance in rodent models, treatment with renin–angiotensin system (RAS) inhibitors, such as Lisinopril, have highly mixed results in humans, likely, in part, due to genetic variation in human populations. To date, the genetic determinants of respo...
Autores principales: | Gabrawy, Mariann M., Khosravian, Nick, Morcos, George S., Morozova, Tatiana V., Jezek, Meagan, Walston, Jeremy D., Huang, Wen, Abadir, Peter M., Leips, Jeff |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775566/ https://www.ncbi.nlm.nih.gov/pubmed/35052483 http://dx.doi.org/10.3390/genes13010143 |
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