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Ionizing Radiation Activates Mitochondrial Function in Osteoclasts and Causes Bone Loss in Young Adult Male Mice

The damaging effects of ionizing radiation (IR) on bone mass are well-documented in mice and humans and are most likely due to increased osteoclast number and function. However, the mechanisms leading to inappropriate increases in osteoclastic bone resorption are only partially understood. Here, we...

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Detalles Bibliográficos
Autores principales: Richardson, Kimberly K., Ling, Wen, Krager, Kimberly, Fu, Qiang, Byrum, Stephanie D., Pathak, Rupak, Aykin-Burns, Nukhet, Kim, Ha-Neui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775597/
https://www.ncbi.nlm.nih.gov/pubmed/35054859
http://dx.doi.org/10.3390/ijms23020675