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Schwannoma Gene Therapy via Adeno-Associated Viral Vector Delivery of Apoptosis-Associated Speck-like Protein Containing CARD (ASC): Preclinical Efficacy and Safety

Schwannomas are tumors derived from Schwann-lineage cells, cells that protect and support myelinated nerves in the peripheral nervous system. They are typically slow-growing, encapsulated and benign. These tumors develop along peripheral, spinal and cranial nerves causing pain, sensory-motor dysfunc...

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Detalles Bibliográficos
Autores principales: Ahmed, Sherif G., Maguire, Casey A., Cao, Shiliang Alice, Brenner, Gary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775599/
https://www.ncbi.nlm.nih.gov/pubmed/35055004
http://dx.doi.org/10.3390/ijms23020819