Reduced DNAJC3 Expression Affects Protein Translocation across the ER Membrane and Attenuates the Down-Modulating Effect of the Translocation Inhibitor Cyclotriazadisulfonamide

One of the reported substrates for the endoplasmic reticulum (ER) translocation inhibitor cyclotriazadisulfonamide (CADA) is DNAJC3, a chaperone of the unfolded protein response during ER stress. In this study, we investigated the impact of altered DNAJC3 protein levels on the inhibitory activity of...

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Detalles Bibliográficos
Autores principales: Pauwels, Eva, Provinciael, Becky, Camps, Anita, Hartmann, Enno, Vermeire, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775681/
https://www.ncbi.nlm.nih.gov/pubmed/35054769
http://dx.doi.org/10.3390/ijms23020584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775681/
https://www.ncbi.nlm.nih.gov/pubmed/35054769
http://dx.doi.org/10.3390/ijms23020584

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