PKM2 Modulation in Head and Neck Squamous Cell Carcinoma

The enzyme pyruvate kinase M2 (PKM2) plays a major role in the switch of tumor cells from oxidative phosphorylation to aerobic glycolysis, one of the hallmarks of cancer. Different allosteric inhibitors or activators and several posttranslational modifications regulate its activity. Head and neck sq...

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Detalles Bibliográficos
Autores principales: Boschert, Verena, Teusch, Jonas, Müller-Richter, Urs D. A., Brands, Roman C., Hartmann, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775697/
https://www.ncbi.nlm.nih.gov/pubmed/35054968
http://dx.doi.org/10.3390/ijms23020775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775697/
https://www.ncbi.nlm.nih.gov/pubmed/35054968
http://dx.doi.org/10.3390/ijms23020775

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