Cargando…

PKM2 Modulation in Head and Neck Squamous Cell Carcinoma

The enzyme pyruvate kinase M2 (PKM2) plays a major role in the switch of tumor cells from oxidative phosphorylation to aerobic glycolysis, one of the hallmarks of cancer. Different allosteric inhibitors or activators and several posttranslational modifications regulate its activity. Head and neck sq...

Descripción completa

Detalles Bibliográficos
Autores principales:	Boschert, Verena, Teusch, Jonas, Müller-Richter, Urs D. A., Brands, Roman C., Hartmann, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775697/ https://www.ncbi.nlm.nih.gov/pubmed/35054968 http://dx.doi.org/10.3390/ijms23020775

Ejemplares similares

The Influence of Met Receptor Level on HGF-Induced Glycolytic Reprogramming in Head and Neck Squamous Cell Carcinoma
por: Boschert, Verena, et al.
Publicado: (2020)

HGF-Induced PD-L1 Expression in Head and Neck Cancer: Preclinical and Clinical Findings
por: Boschert, Verena, et al.
Publicado: (2020)

Merkel Cell Carcinoma of the Head and Neck: Recommendations for Diagnostics and Treatment
por: Müller-Richter, Urs Dietmar Achim, et al.
Publicado: (2017)

Multi-kinase inhibitors and cisplatin for head and neck cancer treatment in vitro
por: Brands, Roman C., et al.
Publicado: (2019)

Comprehensive Geriatric Assessment and Quality of Life Aspects in Patients with Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC)
por: Winter, Anna, et al.
Publicado: (2023)

MicroRNA as a Novel Modulator in Head and Neck Squamous Carcinoma
por: Chen, Li-Hsin, et al.
Publicado: (2010)

EGFR modulates complement activation in head and neck squamous cell carcinoma
por: Abu-Humaidan, Anas H. A., et al.
Publicado: (2020)

An adult spindle cell rhabdomyosarcoma in the head and neck region with long-term survival: a case report
por: Hartmann, Stefan, et al.
Publicado: (2014)

To screen or not to screen: Reply to “Long-term results of an endoscopic screening program for superficial esophageal cancer in patients with head and neck squamous cell carcinoma”
por: van Tilburg, Laurelle, et al.
Publicado: (2022)

Mammary analogue secretory carcinoma of a salivary gland of the hard palate with contralateral cervical lymph node metastases: A case report
por: Straub, Anton, et al.
Publicado: (2021)

Cisplatin effect on head and neck squamous cell carcinoma cells is modulated by ERK1/2 protein kinases
por: Bostan, Marinela, et al.
Publicado: (2019)

Immunotherapy in head and neck squamous cell carcinoma and rare head and neck malignancies
por: Cavalieri, Stefano, et al.
Publicado: (2021)

Protein-Based Oncopanel as Addition to Target Sequencing in Head and Neck Squamous Cell Carcinoma to Individualize Treatment Decisions
por: von Witzleben, Adrian, et al.
Publicado: (2022)

Mediation of PKM2-dependent glycolytic and non-glycolytic pathways by ENO2 in head and neck cancer development
por: Gao, Lixia, et al.
Publicado: (2023)

Accuracy of 18-F Fluorodeoxyglucose Positron Emission Tomographic/Computed Tomographic Imaging in Primary Staging of Squamous Cell Carcinoma of the Oral Cavity
por: Linz, Christian, et al.
Publicado: (2021)

Cutaneous Squamous Cell Carcinoma of the Head and Neck
por: Gurudutt, Vivek V., et al.
Publicado: (2011)

Hypoxia in Head and Neck Squamous Cell Carcinoma
por: Li, John Zenghong, et al.
Publicado: (2012)

Immunotherapy for head and neck squamous cell carcinoma
por: Fuereder, Thorsten
Publicado: (2016)

Immunotherapy for Head and Neck Squamous Cell Carcinoma
por: Moskovitz, Jessica, et al.
Publicado: (2018)

Exosomes in Head and Neck Squamous Cell Carcinoma
por: Xiao, Cheng, et al.
Publicado: (2019)

Can Intensity-Modulated-Radiotherapy Reduce Toxicity in Head and Neck Squamous Cell Carcinoma?
por: van der Veen, Julie, et al.
Publicado: (2017)

The mTOR Pathway Regulates PKM2 to Affect Glycolysis in Esophageal Squamous Cell Carcinoma
por: Xiaoyu, He, et al.
Publicado: (2018)

SUMOylation of HSP27 regulates PKM2 to promote esophageal squamous cell carcinoma progression
por: Zhang, Xiao, et al.
Publicado: (2020)

Microsatellite instability in squamous cell carcinoma of the head and neck.
por: Field, J. K., et al.
Publicado: (1995)

Docetaxel in the treatment of squamous cell carcinoma of the head and neck
por: Rapidis, Alexander, et al.
Publicado: (2008)

Mononuclear phagocytes in head and neck squamous cell carcinoma
por: Kross, Kenneth Wilfried, et al.
Publicado: (2009)

Molecular profiling of head and neck squamous cell carcinoma
por: Feldman, Rebecca, et al.
Publicado: (2015)

Advances in the management of squamous cell carcinoma of the head and neck
por: Machiels, Jean-Pascal, et al.
Publicado: (2014)

Microvessel density in head and neck squamous cell carcinoma
por: Szafarowski, Tomasz, et al.
Publicado: (2018)

Head and Neck Squamous Cell Carcinoma: Epigenetic Landscape
por: Romanowska, Kamila, et al.
Publicado: (2020)

EGFR Mutations in Head and Neck Squamous Cell Carcinoma
por: Nair, Sindhu, et al.
Publicado: (2022)

Preclinical models in head and neck squamous cell carcinoma
por: Chaves, Patricia, et al.
Publicado: (2023)

Taxanes in the Treatment of Head and Neck Squamous Cell Carcinoma
por: Hsieh, Ching-Yun, et al.
Publicado: (2023)

Differential expression profiling of head and neck squamous cell carcinoma (HNSCC)
por: Lemaire, F, et al.
Publicado: (2003)

Histogram analysis parameters of apparent diffusion coefficient reflect tumor cellularity and proliferation activity in head and neck squamous cell carcinoma
por: Surov, Alexey, et al.
Publicado: (2018)

Soluble HER-2 in Patients with Head and Neck Squamous Cell Carcinoma
por: Khademi, Bijan, et al.
Publicado: (2013)

Role of IGF2BPs in head and neck squamous cell carcinoma
por: Wu, Kainan, et al.
Publicado: (2022)

PKM2 and cancer: The function of PKM2 beyond glycolysis
por: DONG, GAOCHAO, et al.
Publicado: (2016)

Loss of HOP tumour suppressor expression in head and neck squamous cell carcinoma
por: Lemaire, F, et al.
Publicado: (2004)

CT Texture Analysis—Correlations With Histopathology Parameters in Head and Neck Squamous Cell Carcinomas
por: Meyer, Hans-Jonas, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_crbc0nsugb4448n8c3vho3qla6