Control of Expression of Key Cell Cycle Enzymes Drives Cell Line-Specific Functions of CDK7 in Human PDAC Cells

Inhibition of the dual function cell cycle and transcription kinase CDK7 is known to affect the viability of cancer cells, but the mechanisms underlying cell line-specific growth control remain poorly understood. Here, we employed a previously developed, highly specific small molecule inhibitor that...

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Detalles Bibliográficos
Autores principales: Kolloch, Lina, Kreinest, Teresa, Meisterernst, Michael, Oeckinghaus, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775745/
https://www.ncbi.nlm.nih.gov/pubmed/35054996
http://dx.doi.org/10.3390/ijms23020812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775745/
https://www.ncbi.nlm.nih.gov/pubmed/35054996
http://dx.doi.org/10.3390/ijms23020812

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