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Control of Expression of Key Cell Cycle Enzymes Drives Cell Line-Specific Functions of CDK7 in Human PDAC Cells
Inhibition of the dual function cell cycle and transcription kinase CDK7 is known to affect the viability of cancer cells, but the mechanisms underlying cell line-specific growth control remain poorly understood. Here, we employed a previously developed, highly specific small molecule inhibitor that...
Autores principales: | Kolloch, Lina, Kreinest, Teresa, Meisterernst, Michael, Oeckinghaus, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775745/ https://www.ncbi.nlm.nih.gov/pubmed/35054996 http://dx.doi.org/10.3390/ijms23020812 |
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