Small Heat Shock Protein 22 Improves Cognition and Learning in the Tauopathic Brain

The microtubule-associated protein tau pathologically accumulates and aggregates in Alzheimer’s disease (AD) and other tauopathies, leading to cognitive dysfunction and neuronal loss. Molecular chaperones, like small heat-shock proteins (sHsps), can help deter the accumulation of misfolded proteins,...

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Detalles Bibliográficos
Autores principales: Rodriguez Ospina, Santiago, Blazier, Danielle M., Criado-Marrero, Marangelie, Gould, Lauren A., Gebru, Niat T., Beaulieu-Abdelahad, David, Wang, Xinming, Remily-Wood, Elizabeth, Chaput, Dale, Stevens, Stanley, Uversky, Vladimir N., Bickford, Paula C., Dickey, Chad A., Blair, Laura J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775832/
https://www.ncbi.nlm.nih.gov/pubmed/35055033
http://dx.doi.org/10.3390/ijms23020851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775832/
https://www.ncbi.nlm.nih.gov/pubmed/35055033
http://dx.doi.org/10.3390/ijms23020851

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