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Small Heat Shock Protein 22 Improves Cognition and Learning in the Tauopathic Brain

The microtubule-associated protein tau pathologically accumulates and aggregates in Alzheimer’s disease (AD) and other tauopathies, leading to cognitive dysfunction and neuronal loss. Molecular chaperones, like small heat-shock proteins (sHsps), can help deter the accumulation of misfolded proteins,...

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Detalles Bibliográficos
Autores principales:	Rodriguez Ospina, Santiago, Blazier, Danielle M., Criado-Marrero, Marangelie, Gould, Lauren A., Gebru, Niat T., Beaulieu-Abdelahad, David, Wang, Xinming, Remily-Wood, Elizabeth, Chaput, Dale, Stevens, Stanley, Uversky, Vladimir N., Bickford, Paula C., Dickey, Chad A., Blair, Laura J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775832/ https://www.ncbi.nlm.nih.gov/pubmed/35055033 http://dx.doi.org/10.3390/ijms23020851

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