Bifunctional Opioid/Melanocortin Peptidomimetics for Use in Neuropathic Pain: Variation in the Type and Length of the Linker Connecting the Two Pharmacophores

Based on the mechanism of neuropathic pain induction, a new type of bifunctional hybrid peptidomimetics was obtained for potential use in this type of pain. Hybrids consist of two types of pharmacophores that are connected by different types of linkers. The first pharmacophore is an opioid agonist,...

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Detalles Bibliográficos
Autores principales: Witkowska, Ewa, Godlewska, Magda, Osiejuk, Jowita, Gątarz, Sandra, Wileńska, Beata, Kosińska, Katarzyna, Starnowska-Sokół, Joanna, Piotrowska, Anna, Lipiński, Piotr F. J., Matalińska, Joanna, Dyniewicz, Jolanta, Halik, Paweł K., Gniazdowska, Ewa, Przewlocka, Barbara, Misicka, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775902/
https://www.ncbi.nlm.nih.gov/pubmed/35054860
http://dx.doi.org/10.3390/ijms23020674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775902/
https://www.ncbi.nlm.nih.gov/pubmed/35054860
http://dx.doi.org/10.3390/ijms23020674

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