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Impact of ER Stress and ER-Mitochondrial Crosstalk in Huntington’s Disease

Accumulation of misfolded proteins is a common phenomenon of several neurodegenerative diseases. The misfolding of proteins due to abnormal polyglutamine (PolyQ) expansions are linked to the development of PolyQ diseases including Huntington’s disease (HD). Though the genetic basis of PolyQ repeats...

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Detalles Bibliográficos
Autores principales: Maity, Shuvadeep, Komal, Pragya, Kumar, Vaishali, Saxena, Anshika, Tungekar, Ayesha, Chandrasekar, Vaani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775980/
https://www.ncbi.nlm.nih.gov/pubmed/35054963
http://dx.doi.org/10.3390/ijms23020780