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Extracellular Calcium Receptor as a Target for Glutathione and Its Derivatives

Extracellular glutathione (GSH) and oxidized glutathione (GSSG) can modulate the function of the extracellular calcium sensing receptor (CaSR). The CaSR has a binding pocket in the extracellular domain of CaSR large enough to bind either GSH or GSSG, as well as the naturally occurring oxidized deriv...

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Detalles Bibliográficos
Autores principales: Goralski, Thomas, Ram, Jeffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776003/
https://www.ncbi.nlm.nih.gov/pubmed/35054903
http://dx.doi.org/10.3390/ijms23020717