In Vitro Evaluation of Bis-3-Chloropiperidines as RNA Modulators Targeting TAR and TAR-Protein Interaction

After a long limbo, RNA has gained its credibility as a druggable target, fully earning its deserved role in the next generation of pharmaceutical R&D. We have recently probed the trans-activation response (TAR) element, an RNA stem–bulge–loop domain of the HIV-1 genome with bis-3-chloropiperidi...

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Detalles Bibliográficos
Autores principales: Sosic, Alice, Olivato, Giulia, Carraro, Caterina, Göttlich, Richard, Fabris, Dan, Gatto, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776071/
https://www.ncbi.nlm.nih.gov/pubmed/35054766
http://dx.doi.org/10.3390/ijms23020582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776071/
https://www.ncbi.nlm.nih.gov/pubmed/35054766
http://dx.doi.org/10.3390/ijms23020582

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