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A Toxoplasma gondii Oxopurine Transporter Binds Nucleobases and Nucleosides Using Different Binding Modes

Toxoplasma gondii is unable to synthesize purines de novo, instead salvages them from its environment, inside the host cell, for which they need high affinity carriers. Here, we report the expression of a T. gondii Equilibrative Nucleoside Transporter, Tg244440, in a Trypanosoma brucei strain from w...

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Detalles Bibliográficos
Autores principales: Campagnaro, Gustavo D., Elati, Hamza A. A., Balaska, Sofia, Martin Abril, Maria Esther, Natto, Manal J., Hulpia, Fabian, Lee, Kelly, Sheiner, Lilach, Van Calenbergh, Serge, de Koning, Harry P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776092/
https://www.ncbi.nlm.nih.gov/pubmed/35054895
http://dx.doi.org/10.3390/ijms23020710