Reactive Oxygen Species Production Is Responsible for Antineoplastic Activity of Osmium, Ruthenium, Iridium and Rhodium Half-Sandwich Type Complexes with Bidentate Glycosyl Heterocyclic Ligands in Various Cancer Cell Models

Platinum complexes are used in chemotherapy, primarily as antineoplastic agents. In this study, we assessed the cytotoxic and cytostatic properties of a set of osmium(II), ruthenium(II), iridium(III) and rhodium(III) half-sandwich-type complexes with bidentate monosaccharide ligands. We identified 5...

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Detalles Bibliográficos
Autores principales: Kacsir, István, Sipos, Adrienn, Bényei, Attila, Janka, Eszter, Buglyó, Péter, Somsák, László, Bai, Péter, Bokor, Éva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776094/
https://www.ncbi.nlm.nih.gov/pubmed/35054999
http://dx.doi.org/10.3390/ijms23020813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776094/
https://www.ncbi.nlm.nih.gov/pubmed/35054999
http://dx.doi.org/10.3390/ijms23020813

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