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Reactive Oxygen Species Production Is Responsible for Antineoplastic Activity of Osmium, Ruthenium, Iridium and Rhodium Half-Sandwich Type Complexes with Bidentate Glycosyl Heterocyclic Ligands in Various Cancer Cell Models
Platinum complexes are used in chemotherapy, primarily as antineoplastic agents. In this study, we assessed the cytotoxic and cytostatic properties of a set of osmium(II), ruthenium(II), iridium(III) and rhodium(III) half-sandwich-type complexes with bidentate monosaccharide ligands. We identified 5...
Autores principales: | Kacsir, István, Sipos, Adrienn, Bényei, Attila, Janka, Eszter, Buglyó, Péter, Somsák, László, Bai, Péter, Bokor, Éva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776094/ https://www.ncbi.nlm.nih.gov/pubmed/35054999 http://dx.doi.org/10.3390/ijms23020813 |
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