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Dracunculin Inhibits Adipogenesis in Human Bone Marrow-Derived Mesenchymal Stromal Cells by Activating AMPK and Wnt/β-Catenin Signaling

Increased bone marrow adiposity is widely observed in patients with obesity and osteoporosis and reported to have deleterious effects on bone formation. Dracunculin (DCC) is a coumarin isolated from Artemisia spp. but, until now, has not been studied for its bioactive potential except antitrypanosom...

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Detalles Bibliográficos
Autores principales: Karadeniz, Fatih, Oh, Jung Hwan, Jo, Hyun Jin, Yang, Jiho, Lee, Hyunjung, Seo, Youngwan, Kong, Chang-Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776130/
https://www.ncbi.nlm.nih.gov/pubmed/35054838
http://dx.doi.org/10.3390/ijms23020653